BPC-157 (Body Protection Compound-157) is a synthetic peptide derived from a protein found in gastric juice. It has gained substantial interest in scientific communities for its powerful regenerative and anti-inflammatory effects in both in vitro and in vivo research settings.

This peptide is widely studied for its ability to accelerate wound healing, promote tendon and ligament repair, and reduce gastrointestinal inflammation, making it a top-tier candidate for research into tissue regeneration, chronic injury, and autoimmune conditions.

BPC-157 is presented in lyophilized powder form, ideal for reconstitution with bacteriostatic water for controlled laboratory experimentation. This compound is strictly for research purposes only and is not intended for human consumption.

What is BPC-157?

BPC-157 is a 15-amino acid peptide sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) derived from a protein found in the human gastric system. Despite being synthetically constructed, its effects are deeply rooted in the body’s own natural healing mechanisms.

In experimental models, BPC-157 appears to enhance angiogenesis (formation of new blood vessels), regulate nitric oxide production, promote cellular migration, and accelerate the healing of soft tissue — without adverse systemic effects.

Unlike many research peptides, BPC-157 is known to remain stable in gastric environments, making it suitable for oral or injectable research protocols depending on the experiment.

Potential Research Benefits of BPC-157:

These theoretical effects are based on preclinical studies. Product is not approved for therapeutic use.

1. Accelerated Healing of Tendons and Ligaments:

BPC-157 has shown the ability to stimulate fibroblast migration and tendon outgrowth in injured animal models. Studies show it significantly enhances the healing process in Achilles tendons, medial collateral ligaments (MCL), and rotator cuff injuries.

• A study published in Muscle, Ligaments and Tendons Journal demonstrated rapid tendon-to-bone healing in rats with surgically repaired MCLs when BPC-157 was administered.

2. Gastrointestinal Protection:

Given its origin in gastric proteins, BPC-157 is heavily studied in digestive health research. It has been shown to protect and repair stomach ulcers, counteract NSAID-induced damage, and restore intestinal integrity in models of inflammatory bowel disease (IBD).

• Animal studies indicate BPC-157 can counteract gastric lesions induced by ibuprofen and alcohol, significantly reducing bleeding and ulceration.

3. Nerve Regeneration and Neurological Repair:

BPC-157 has been observed to support nerve regeneration in damaged central and peripheral nervous systems. It may help restore locomotion and nerve functionality post-injury by stimulating neurovascular growth and reducing neuroinflammation.

• A study in the Journal of Physiology highlighted BPC-157’s role in improving functional recovery in rats after traumatic brain injury.

4. Cardiovascular Research Applications:

Research has shown BPC-157 may help normalize blood pressure, prevent arrhythmias, and improve cardiac recovery post-injury. It’s thought to stabilize nitric oxide (NO) pathways, balancing vasodilation and constriction in damaged vascular tissues.

5. Muscle and Joint Recovery:

In rodent studies, BPC-157 showed reduced inflammation in muscle tissue and joints following injury. Its capacity to increase blood flow and modulate cytokine release suggests it may be helpful in arthritis and joint degeneration models.

6. Liver and Organ Regeneration:

Liver toxicity studies in mice have shown BPC-157 reduced damage from paracetamol (acetaminophen) and alcohol-induced hepatotoxicity. Researchers believe it enhances hepatocyte survival, possibly through modulation of eNOS and angiogenic factors.

Scientific Studies and Data:

• Pavlovic et al., 2010 (PubMed): Demonstrated significant healing in rat Achilles tendon injuries after BPC-157 injections. Healing was faster and more complete versus control groups.

• Sikiric et al., 2014: Studied BPC-157’s effects on NSAID-induced gut lesions. The peptide prevented and healed lesions from indomethacin exposure in animal models.

• Klicek et al., 2011: In a study on rats, BPC-157 reversed alcohol-induced liver and GI lesions, restored endothelial function, and improved vascularization.

• Strinic et al., 2017: Showed BPC-157 improved functional recovery post-spinal cord injury by supporting neuronal survival and reducing oxidative stress.

Common Experimental Uses:

• Tendon Repair Models (Achilles, rotator cuff, knee ligaments)

• Intestinal Permeability Studies (IBD, Crohn’s, colitis)

• Neurological Injury Research (peripheral nerve crush, traumatic brain injury)

• Vascular Studies (angiogenesis, cardiac ischemia models)

• Wound Healing Assays

Reconstitution & Storage

• Reconstitution: Add 1mL–2mL of bacteriostatic water to the vial to reach 5–10mg/mL solution.

• Storage: Store lyophilized powder in the fridge (2–8°C). Once reconstituted, keep refrigerated and use within 30 days for maximum stability.

• Handling: Use sterile syringes and follow aseptic technique to maintain compound integrity.

Observed Side Effects (Research Context):

In animal studies, BPC-157 has exhibited a very low toxicity profile. No significant organ damage or systemic issues have been reported. Mild irritation or immune response may occur if injected improperly, though most models tolerated repeated administration well.

Legal & Compliance Notice:

This product is sold strictly for research and laboratory use only. It is not approved by the TGA, FDA, or any other regulatory authority for human use. All buyers must confirm they are authorized to handle, store, and study research chemicals in their jurisdiction.